Automatic semantic priming abnormalities in schizophrenia

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Automatic semantic priming abnormalities in schizophrenia.

Abnormal activation of semantic networks characterizes schizophrenia and can be studied using the N400 event-related potential (ERP). N400 is elicited by words that are not primed by the preceding context and provides a direct measure of the neural mechanisms underlying semantic priming. Semantic priming refers to facilitated semantic processing gained through pre-exposure to semantic context, ...

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N400 and automatic semantic processing abnormalities in patients with schizophrenia.

BACKGROUND One factor hypothesized to underlie thinking disturbance in patients with schizophrenia is abnormal or disinhibited automatic spreading activation of semantic networks, which can be assessed using the N400 event-related potential. N400 is a negative-going component elicited at about 400 milliseconds following semantic stimuli that are not primed by the preceding context. Semantic pri...

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ERP abnormalities during semantic processing in schizophrenia.

To examine the neurophysiological and cognitive characteristics of thought disturbance in schizophrenic patients, we examined the amplitude, latency, and topography of a specific event-related brain potential (ERP), the N400, which is elicited by semantically incongruent words and phrases. Twelve chronic schizophrenic patients and twelve age-matched control subjects read sentences presented vis...

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Priming production: Neural evidence for enhanced automatic semantic activity preceding language production in schizophrenia

Introduction Lexico-semantic disturbances are considered central to schizophrenia. Clinically, their clearest manifestation is in language production. However, most studies probing their underlying mechanisms have used comprehension or categorization tasks. Here, we probed automatic semantic activity prior to language production in schizophrenia using event-related potentials (ERPs). Methods ...

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Excessive Attractor Instability Accounts for Semantic Priming in Schizophrenia

One of the most pervasive findings in studies of schizophrenics with thought disorders is their peculiar pattern of semantic priming, which presumably reflects abnormal associative processes in the semantic system of these patients. Semantic priming is manifested by faster and more accurate recognition of a word-target when preceded by a semantically related prime, relative to an unrelated prim...

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ژورنال

عنوان ژورنال: International Journal of Psychophysiology

سال: 2010

ISSN: 0167-8760

DOI: 10.1016/j.ijpsycho.2009.12.003